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Comprehensive phenotyping of human peripheral blood B lymphocytes in pathological conditions
Author(s) -
Carsetti Rita,
Corrente Francesco,
Capponi Claudia,
Mirabella Mattia,
Cascioli Simona,
Palomba Patrizia,
Bertaina Valentina,
Pagliara Daria,
Colucci Manuela,
Piano Mortari Eva
Publication year - 2022
Publication title -
cytometry part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.316
H-Index - 90
eISSN - 1552-4930
pISSN - 1552-4922
DOI - 10.1002/cyto.a.24518
Subject(s) - peripheral blood , flow cytometry , compartment (ship) , peripheral , mass cytometry , pathological , cell , b cell , blood cell , immunology , medicine , pathology , biology , phenotype , genetics , antibody , oceanography , gene , geology
Several diseases are associated with alterations of the B‐cell compartment. Knowing how to correctly identify by flow cytometry the distribution of B‐cell populations in the peripheral blood is important to help in the early diagnosis. In the accompanying article we describe how to identify the different B‐cell subsets in the peripheral blood of healthy donors. Here we show a few examples of diseases that cause dysregulation of the B‐cell compartment.