English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Zendy Plus

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Zendy Tools

Zendy Open

Medication adherence correlates with morbidity and mortality in patients with chronic heart failure ( CHF ), but is difficult to assess. We conducted a retrospective methodological cohort study in 3,808  CHF  patients, calculating adherence as proportion of days covered ( PDC ) utilizing claims data from 2010 to 2015. We aimed to compare different parameters’ influence on the  PDC  of elderly  CHF  patients exemplifying a complex chronic disease. Investigated parameters were the assumed prescribed daily dose ( PDD ), stockpiling, and periods of hospital stay. Thereby, we investigated a new approach using the  PDD  assigned to different percentiles. The different dose assumptions had the biggest influence on the  PDC , with variations from 41.9% to 83.7%. Stockpiling and hospital stays increased the values slightly. These results queries that a reliable  PDC  can be calculated with an assumed  PDD . Hence, results based on an assumed  PDD  have to be interpreted carefully and should be presented with sensitivity analyses to show the  PDC 's possible range.

Comparison of Different Strategies to Measure Medication Adherence via Claims Data in Patients With Chronic Heart Failure