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An evolutionary framework for treating pediatric sarcomas
Author(s) -
Reed Damon R.,
Metts Jonathan,
Pressley Mariyah,
Fridley Brooke L.,
Hayashi Masanori,
Isakoff Michael S.,
Loeb David M.,
Makanji Rikesh,
Roberts Ryan D.,
Trucco Matteo,
Wagner Lars M.,
Alexandrow Mark G.,
Gatenby Robert A.,
Brown Joel S.
Publication year - 2020
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/cncr.32777
Subject(s) - medicine , leverage (statistics) , pediatric cancer , cancer , intensive care medicine , sarcoma , surgery , pathology , artificial intelligence , computer science
Lessons from extinction can be used in trials designed to pursue a cure for cancer. When cancer cannot be cured, similar strategies may be unwise, and strategies that leverage the adaptations of cancer to therapy should be considered.