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Photo‐Induced Ruthenium‐Catalyzed C−H Benzylations and Allylations at Room Temperature
Author(s) -
Struwe Julia,
Korvorapun Korkit,
Zangarelli Agnese,
Ackermann Lutz
Publication year - 2021
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.202103077
Subject(s) - ruthenium , catalysis , combinatorial chemistry , chemistry , scope (computer science) , photoredox catalysis , robustness (evolution) , photochemistry , organic chemistry , computer science , photocatalysis , biochemistry , gene , programming language
Abstract The ruthenium‐catalyzed synthesis of diarylmethane compounds was realized under exceedingly mild photoredox conditions without the use of exogenous photocatalysts. The versatility and robustness of the ruthenium‐catalyzed C−H benzylation was reflected by an ample scope, including multifold C−H functionalizations, as well as transformable pyrazoles, imidates and sensitive nucleosides. Mechanistic studies were indicative of a photoactive cyclometalated ruthenium complex, which also enabled versatile C−H allylations.