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Reversible Self‐Assembly of Gold Nanoparticles Based on Co‐Functionalization with Zwitterionic and Cationic Binding Motifs **
Author(s) -
He Huibin,
Rudolph Kevin,
Ostwaldt JanErik,
Voskuhl Jens,
Hirschhäuser Christoph,
Niemeyer Jochen
Publication year - 2021
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.202102457
Subject(s) - cationic polymerization , surface modification , carboxylate , chemistry , nanoparticle , colloidal gold , pyrrole , combinatorial chemistry , self assembly , polymer chemistry , inorganic chemistry , nanotechnology , stereochemistry , organic chemistry , materials science
Abstract We report a pH‐ and temperature‐controlled reversible self‐assembly of Au‐nanoparticles (AuNPs) in water, based on their surface modification with cationic guanidiniocarbonyl pyrrole (GCP) and zwitterionic guanidiniocarbonyl pyrrole carboxylate (GCPZ) binding motifs. When both binding motifs are installed in a carefully balanced ratio, the resulting functionalized AuNPs self‐assemble at pH 1, pH 7 and pH 13, whereas they disassemble at pH 3 and pH 11. Further disassembly can be achieved at elevated temperatures at pH 1 and pH 13. Thus, we were able to prepare functionalized nanoparticles that can be assembled/disassembled in seven alternating regimes, simply controlled by pH and temperature.