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A Convenient Formal [4+2] Heterocylization Route to Bis(triflyl)tetrahydroquinolines
Author(s) -
LázaroMilla Carlos,
Almendros Pedro
Publication year - 2021
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.202102254
Subject(s) - quinoline , combinatorial chemistry , catalysis , chemistry , formal synthesis , functional group , organic chemistry , polymer
Abstract We report the sustainable and efficient synthesis of a new type of quinoline derivatives bearing one or two SO 2 CF 3 groups. The protocol is metal‐, catalyst‐ and irradiation‐free, involves the use of readily available and stable precursors, and avoids the formation of side products. Also, the mild conditions of the process allow the tolerance of a wide range of functional groups.