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Catalyst Deactivation During Rhodium Complex‐Catalyzed Propargylic C−H Activation
Author(s) -
Möller Saskia,
Jannsen Nora,
Rüger Julia,
Drexler HansJoachim,
Horstmann Moritz,
Bauer Felix,
Breit Bernhard,
Heller Detlef
Publication year - 2021
Publication title -
chemistry – a european journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.687
H-Index - 242
eISSN - 1521-3765
pISSN - 0947-6539
DOI - 10.1002/chem.202102219
Subject(s) - rhodium , catalysis , chemistry , allylic rearrangement , reaction mechanism , raman spectroscopy , combinatorial chemistry , photochemistry , organic chemistry , physics , optics
Detailed mechanistic investigations on our previously reported synthesis of branched allylic esters by the rhodium complex‐catalyzed propargylic C−H activation have been carried out. Based on initial mechanistic studies, we present herein more detailed investigations of the reaction mechanism. For this, various analytical (NMR, X‐ray crystal structure analysis, Raman) and kinetic methods were used to characterize the formation of intermediates under the reaction conditions. The knowledge obtained by this was used to further optimize the previous conditions and generate a more active catalytic system.