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Innovation of Expanded‐Bed Adsorption by Integrating Simulated Moving‐Bed Technology
Author(s) -
Pathapati Trinath,
Rutze Dennis N.,
Wit Pieter,
Boer Piet,
Zaalberg Menne
Publication year - 2018
Publication title -
chemical engineering and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.403
H-Index - 81
eISSN - 1521-4125
pISSN - 0930-7516
DOI - 10.1002/ceat.201800293
Subject(s) - simulated moving bed , process engineering , adsorption , process (computing) , fluidized bed , chromatography , chemistry , biochemical engineering , engineering , computer science , waste management , organic chemistry , operating system
Bio‐based industries need efficient downstream solutions to process complex streams. This was addressed through a technology integration approach, where expanded‐bed adsorption (EBA) is integrated with simulated moving‐bed (SMB) technology. Current work involved adaptation of an SMB apparatus and control principle to implement expanded‐bed level control. As an outcome, EBA‐SMB technology was successfully applied for purification of γ ‐aminobutyric acid (GABA). This resulted in two‐fold increase in productivity and a GABA purity ≥ 92 % in one step from unclarified fermentation broth, compared to ≥ 93 % purity in case of clarified broth and packed‐bed SMB. These results proved that EBA‐SMB technology is able to enhance process efficiency and economics of bioprocesses.