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Aminotriazole Mn(I) Complexes as Effective Catalysts for Transfer Hydrogenation of Ketones
Author(s) -
MartínezFerraté Oriol,
Werlé Christophe,
Franciò Giancarlo,
Leitner Walter
Publication year - 2018
Publication title -
chemcatchem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.497
H-Index - 106
eISSN - 1867-3899
pISSN - 1867-3880
DOI - 10.1002/cctc.201800953
Subject(s) - catalysis , transfer hydrogenation , chemistry , manganese , substrate (aquarium) , ligand (biochemistry) , combinatorial chemistry , base (topology) , medicinal chemistry , organic chemistry , photochemistry , ruthenium , receptor , mathematical analysis , biochemistry , oceanography , mathematics , geology
A catalytic system based on complexes comprising abundant and cheap manganese together with readily available aminotriazole ligands is reported. The new Mn(I) complexes are catalytically competent in transfer hydrogenation of ketones with 2‐propanol as hydrogen source. The reaction proceeds under mild conditions at 80 °C for 20 h with 3 % of catalyst loading using either KO t Bu or NaOH as base. Good to excellent yields were obtained for a wide substrate scope with broad functional group tolerance. The obtained results by varying the substitution pattern of the ligand are consistent with an out‐sphere mechanism for the H‐transfer.