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Key Clinical Message  This report demonstrates a case of atopic dermatitis that was unresponsive to topical steroid therapy. This clinical report highlights the fact that metals used in dental treatment, such as mercury, as well as cross‐reactions between nickel and palladium, may cause systemic hypersensitivity or toxicity.

clinical case reports

Severe dermatitis might be caused by a cross‐reaction between nickel and palladium and dental amalgam resolved following removal of dental restorations