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Key Clinical Message  This case suggests that initiation of  HCV  therapy immediately after liver transplantation with well‐tolerated, all‐oral regimens may achieve a virologic cure in  HCV ‐positive recipients, thus preventing post‐transplant  HCV  recurrence and associated disease progression. This strategy may broaden utilization of  HCV ‐positive donor livers, potentially including  HCV ‐negative transplant recipients.

clinical case reports

An  HCV ‐positive recipient of an  HCV ‐positive donor liver successfully treated before and immediately after liver transplant with daclatasvir, sofosbuvir, and ribavirin