Open AccessCopper deficiency‐related bone marrow changes secondary to long‐term total parenteral nutrition
Author(s) -
Oo Thein Hlaing,
Hu Shimin
Publication year - 2017
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.789
Subject(s) - medicine , gastroenterology , complete blood count , parenteral nutrition , bone marrow , anemia , iron deficiency , surgery , pathology
Key Clinical Message Total parenteral nutrition can be complicated by the marrow sea‐blue histiocytes as well as copper deficiency‐related bone marrow changes. Cytoplasmic vacuoles in the erythroid and myeloid precursors raise the possibility of copper deficiency anemia. If the diagnosis is delayed, the clinical course can be complicated by neurologic deficits.