Open AccessA new case of “de novo” BRCA 1 mutation in a patient with early‐onset breast cancer
Author(s) -
Antonucci Ivana,
Provenzano Martina,
Sorino Luca,
Rodrigues Melissa,
Palka Giandomenico,
Stuppia Liborio
Publication year - 2017
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.718
Subject(s) - medicine , breast cancer , family history , mutation , cancer , disease , oncology , gene , genetics , biology
Key Clinical Message Most of the de novo BRCA 1/2 mutations have been identified in patients with early‐onset breast cancer and without family history of the disease. The identification of these alterations could play a prominent role in the prevention and treatment strategies and may influence clinical management of patients.