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Key Clinical Message  Glucose‐6‐phosphate (G6 PD ) deficiency is the most common human enzyme defect, often presenting with neonatal jaundice and/or acute hemolytic anemia, triggered by oxidizing agents. G6 PD  deficiency is an X‐linked, hereditary disease, mainly affecting men, but should also be considered in females with an oxidative hemolysis.

Glucose‐6‐phosphate dehydrogenase deficiency: not exclusively in males