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Key Clinical Message  Patients with common variable immunodeficiency are prone to infections, and this poses a particular challenge during pregnancy, when the requirement for immunoglobulin (Ig) replacement therapy is even more demanding so as to achieve an effective protection also of the fetus. This case report highlights the benefits observed with subcutaneous IgG self‐administration in the management of common variable immunodeficiency ( CVID ) during pregnancy, in terms of efficacy and safety.

Management of common variable immunodeficiency by subcutaneous IgG self‐administration during pregnancy – a case report