Open AccessMature CD8 + T‐cell clonal expansion in the oral cavity and digestive tract: a severe lymphoid malignancy that mimics Crohn's disease
Author(s) -
Coppo Paul,
Fabiani Bettina,
Marzac Christophe,
Sokol Harry
Publication year - 2016
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.668
Subject(s) - medicine , gastroenterology , lymphoma , pathology , pancolitis , cancer , colonoscopy , colorectal cancer
Key Clinical Message In patients with atypical Crohn's disease features, including severe oral ulcerations and resistance to standard treatment, the possibility of a mature clonal CD8 + T‐cell lymphoproliferative disorder should be investigated. Clinicians should be aware of this differential diagnosis because CD8 + T‐cell lymphoma prognosis can be remarkably favorable upon oral treatment with cyclophosphamide.