Open AccessAdenoid cystic carcinoma of submandibular gland metastatic to great toes: case report and literature review
Author(s) -
Rafael Oana C.,
Paul Doru,
Chen Sheng,
Kraus Dennis
Publication year - 2016
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.635
Subject(s) - medicine , adenoid cystic carcinoma , submandibular gland , pathology , salivary gland , metastasis , carcinoma , cancer
Key Clinical Message Adenoid cystic carcinoma ( ACC ) is a rare malignant tumor of the salivary glands, with higher frequency in the submandibular gland, a prolonged clinical course, and poor long‐term survival. It tends to metastasize to lungs, bone, liver, brain, and rarely to skin. Comprehensive skin examination and appropriate follow‐up is recommended, since cutaneous metastasis represents disease progression, requiring management and prognosis adjustment.