Open AccessHepatotoxicity due to zinc phosphide poisoning in two patients: role of N ‐acetylcysteine
Author(s) -
Oghabian Zohreh,
Afshar Arefeh,
Rahimi Hamid Reza
Publication year - 2016
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.618
Subject(s) - medicine , vomiting , nausea , acetylcysteine , rodenticide , metabolic acidosis , emergency department , toxicity , anesthesia , accidental , antidote , toxicology , biochemistry , chemistry , physics , psychiatry , acoustics , biology , antioxidant
Key Clinical Message Zinc phosphide (Zn 3 P 2 /ZnP) is used as a rodenticide. The most common signs of toxicity are nausea, vomiting, hypotension, and metabolic acidosis; patients presenting such signs are referred to the emergency department (ED) of the hospitals. Therefore, this study aimed to report two cases of hepatotoxicity following accidental and intentional ZnP poisoning and successful management with N ‐acetylcysteine (NAC).