Open AccessHyperacute ischemic stroke without lesions on diffusion‐weighted imaging in a patient treated with rt PA thrombolysis
Author(s) -
Jing Zhen,
Zhang Shijun,
Tang Jingjing,
Xu Anding,
Ruan Yiwen,
Huang Li'an
Publication year - 2014
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.60
Subject(s) - thrombolysis , medicine , recombinant tissue plasminogen activator , tissue plasminogen activator , ischemic stroke , stroke (engine) , diffusion mri , radiology , brain ischemia , ischemia , cardiology , magnetic resonance imaging , myocardial infarction , mechanical engineering , modified rankin scale , engineering
Key Clinical Message We report a comatose patient with severe neurological deficits who was without spontaneous language or movement. He had a good response to recombinant tissue plasminogen activator (rt PA ) thrombolysis even though there were no detectable lesions on diffusion‐weighted imaging ( DWI ). DWI is very sensitive for diagnosing hyperacute ischemic stroke, and rt PA thrombolysis is the best treatment. However, rt PA thrombolysis in ischemic stroke patients without lesions on DWI has rarely been reported.