Open AccessHow atypical can Atypical Hemolytic Uremic Syndrome be?
Author(s) -
Sajan Thomas,
Vinay Srinivasa,
Sonu Nigam,
Alan Parnham
Publication year - 2014
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.59
Subject(s) - medicine , eculizumab , microangiopathic hemolytic anemia , atypical hemolytic uremic syndrome , posterior reversible encephalopathy syndrome , thrombotic microangiopathy , hemodialysis , hemolytic anemia , complication , haemolytic uraemic syndrome , diarrhea , gastroenterology , anemia , pediatrics , thrombotic thrombocytopenic purpura , immunology , complement system , disease , antibody , radiology , magnetic resonance imaging , biochemistry , platelet , chemistry , escherichia coli , gene
Key Clinical Message A 24‐year‐old man with diarrhea found to have acute renal failure with microangiopathic hemolytic anemia (MAHA). A diagnosis of hemolytic uraemic syndrome ( HUS ) was made. He was initiated on plasma exchange and hemodialysis. On day 6, he was started on eculizumab. His renal functions progressively improved. His main complication during eculizumab therapy was hypertension‐related posterior reversible encephalopathy syndrome.