Open AccessCase report: successful retreatment of hepatitis C genotype 1b infection with sofosbuvir + simeprevir in a patient with cirrhosis who had prior virologic relapse after treatment with daclatasvir and asunaprevir
Author(s) -
Safadi Rifaat,
Noviello Stephanie,
Boparai Navdeep,
McPhee Fiona
Publication year - 2016
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.581
Subject(s) - daclatasvir , simeprevir , sofosbuvir , medicine , hepatitis c , cirrhosis , hepatitis c virus , virology , gastroenterology , ribavirin , virus
Key Clinical Message There is currently minimal clinical experience regarding retreatment options for patients failing direct‐acting antiviral combination regimens. Here, we report the outcomes of a HCV genotype 1b‐infected patient with virologic failure following treatment with daclatasvir and asunaprevir, who was successfully retreated with sofosbuvir plus simeprevir.