Open AccessChronic myelomonocytic leukemia presenting with polyserositis due to an immune‐mediated monocyte activation
Author(s) -
Imataki Osamu,
Watanabe Naoki,
Matsumoto Kensuke,
Uemura Makiko
Publication year - 2014
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.55
Subject(s) - monocytosis , medicine , chronic myelomonocytic leukemia , immunology , monocyte , immune system , pleural effusion , bone marrow , myelodysplastic syndromes
Key Clinical Message Monocytosis is often profoundly implicated in chronic myelomonocytic leukemia (CMML). We diagnosed a 63‐year‐old woman with CMML involving heterochronological systemic polyserositis with infiltrating benign monocytes. The patient's pleural effusion was eliminated completely with corticosteroid therapy. We speculate that our case represents an immunological reaction with activated monocytes triggered by infection.