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Key Clinical Message  We treated a case in which multiple astrocytomas of varying grades developed in the irradiation field 24 years after radiation therapy. Differentiation from radiation necrosis based on presurgical diagnostic imaging was difficult; therefore, we feel it is essential to aggressively pursue histological diagnoses to select the optimal treatment method.

A case of multiple radiation‐induced gliomas 24 years after radiation therapy against pituitary adenoma