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Key Clinical Message  Drug–Drug interactions is important when caring for warfarin‐treated patients. We examined the impact on  INR  with coadministration of warfarin and caspofungin and showed no affect on the  INR . Coadministrations of fluconazole lead to a marked increase in  INR . We concluded that administration of caspofungin and warfarin was safe.

clinical case reports

Warfarin treatment and antifungal agent caspofungin for severe fungal infection in a patient previously treated with radiotherapy for oropharyngeal cancer