Open AccessWarfarin treatment and antifungal agent caspofungin for severe fungal infection in a patient previously treated with radiotherapy for oropharyngeal cancer
Author(s) -
Vedtofte Thomas,
Thisted Camilla Heyn,
FriisHansen Lennart
Publication year - 2016
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.469
Subject(s) - caspofungin , medicine , warfarin , fluconazole , voriconazole , antifungal , drug , intensive care medicine , pharmacology , dermatology , atrial fibrillation
Key Clinical Message Drug–Drug interactions is important when caring for warfarin‐treated patients. We examined the impact on INR with coadministration of warfarin and caspofungin and showed no affect on the INR . Coadministrations of fluconazole lead to a marked increase in INR . We concluded that administration of caspofungin and warfarin was safe.