Open AccessAdult hemophagocytic lymphohistiocytosis causing multi organ dysfunction in a patient with multiple autoimmune disorders: when the immune system runs amok
Author(s) -
Fleischmann Robert,
Böhmerle Wolfgang,
Laffert Maximilian,
Jöhrens Korinna,
Mengel Annerose,
Hotter Benjamin,
Lindenberg Robert,
Scheibe Franziska,
Köhnlein Martin,
Bahr Greenwood Tatiana,
Henter Jan Inge,
Meisel Andreas
Publication year - 2016
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.467
Subject(s) - hemophagocytic lymphohistiocytosis , medicine , organ dysfunction , sepsis , immune dysfunction , immune system , immunology , immune dysregulation , multiple organ dysfunction syndrome , systemic inflammatory response syndrome , pathology , disease
Key Clinical Message We report a case of several autoimmune disorders eventually presenting as severe multi organ dysfunction syndrome caused by adult hemophagocytic lymphohistiocytosis ( HLH ). Clinical and laboratory tests might lead to fatal misinterpretation without awareness of its diagnostic evaluation, as HLH shares common features with sepsis and immune‐mediated systemic inflammatory response syndromes.