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Key Clinical Message  We report a case of several autoimmune disorders eventually presenting as severe multi organ dysfunction syndrome caused by adult hemophagocytic lymphohistiocytosis ( HLH ). Clinical and laboratory tests might lead to fatal misinterpretation without awareness of its diagnostic evaluation, as  HLH  shares common features with sepsis and immune‐mediated systemic inflammatory response syndromes.

clinical case reports

Adult hemophagocytic lymphohistiocytosis causing multi organ dysfunction in a patient with multiple autoimmune disorders: when the immune system runs amok