Open AccessInsulin detemir may be less efficacious in patients with nonalcoholic fatty liver disease and hypertriglyceridemia
Author(s) -
Whyte Martin,
Quaglia Alberto,
Hopkins David
Publication year - 2016
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.458
Subject(s) - insulin detemir , medicine , hypertriglyceridemia , nonalcoholic fatty liver disease , diabetes mellitus , liraglutide , insulin , fatty liver , gastroenterology , endocrinology , disease , type 2 diabetes , triglyceride , basal insulin , cholesterol
Key Clinical Message Insulin detemir is commonly used in obese patients with diabetes mellitus as it is considered hepatoselective and causes less weight gain. We describe a relative lack of effectiveness of detemir in patients with significant NAFLD and hypertriglyceridemia, compared to isophane insulin. This may affect how such patients are managed with insulin.