Open AccessSpontaneous remission in three cases of AML M5 with NPM 1 mutation
Author(s) -
Camus Vincent,
Etancelin Pascaline,
Jardin Fabrice,
Lenain Pascal,
Contentin Nathalie,
Daliphard Sylvie,
Buchonnet Gérard,
Lemasle Emilie,
Lanic Hélène,
Leprêtre Stéphane,
Penther Dominique,
Dubois Sydney,
Tilly Hervé,
Bastard Christian,
Stamatoullas Aspasia
Publication year - 2015
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.408
Subject(s) - medicine , myeloid leukemia , complete remission , mutation , chemotherapy , gene , genetics , biology
Key Clinical Message Patients with NPM 1‐mutated AML M5 who develop spontaneous remission ( SR ) after antibiotic therapy at diagnosis seem to form a favorable prognosis and chemo sensitive subtype. We report three cases of AML M5 patients with the same genotype that experienced transient SR and are now leukemia free after standard treatment.