Open AccessAn unusual case of chronic lymphocytic leukemia with trisomy 12 presenting with prolymphocytic transformation and t(8;21)(q22;q22)
Author(s) -
Bhushan Mishi,
Kumar Kirthi R.
Publication year - 2021
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.4059
Subject(s) - prolymphocytic leukemia , medicine , fusion gene , chromosomal translocation , trisomy , chronic lymphocytic leukemia , transformation (genetics) , pathology , cancer research , leukemia , gene , genetics , biology
First report of t(8;21)(q22;q22) in a patient with CLL. RUNX1‐RUNX1T1 fusion gene resulting from the translocation may have played a role in the prolymphocytic transformation.