Open Access
Huffing and twist: Fatal Torsade de pointes associated with Tetrafluoroethane Inhalation and amphetamine use
Author(s) -
Burke Joseph,
Haigney Mark C. P.,
Farasat Morteza,
Mehler Philip S.,
Krantz Mori J.
Publication year - 2021
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.3838
Subject(s) - medicine , torsades de pointes , inhalation , recreational drug , anesthesia , blockade , amphetamine , qt interval , pharmacology , intensive care medicine , drug , dopamine , receptor
Abstract Many volatile chemicals inhaled for a recreational high have a chemical structure similar to chloroform and may lead to Ikr blockade and subsequent torsades de pointes. This is one potential mechanism of action for huffing‐associated sudden death.