Open AccessChronic persistent HHV‐6B infection after sulfasalazine‐induced DRESS with demonstration of HHV‐6 encoded small noncoding RNAs (sncRNAs) in Crohn’s‐like colitis: Case report
Author(s) -
Descamps Vincent,
GautheretDejean Agnès,
Pelletier AnneLaure,
Bonnafous Pascale,
Deschamps Lydia,
Prusty Bhupesh K.
Publication year - 2021
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.3680
Subject(s) - sulfasalazine , medicine , colitis , immunology , eosinophilia , ulcerative colitis , pathology , disease
A sulfasalazine‐induced DRESS (Drug Reactivation with Eosinophilia and Systemic Symptoms) was complicated by a Crohn's‐like colitis. We demonstrated HHV‐6 reactivation with presence of HHV‐6 DNA and small noncoding RNA in colonic lesions. This observation confirms the major role of HHV‐6 reactivation in DRESS manifestations and the importance of looking for HHV‐6 reactivation in DRESS.