Open AccessFlare‐up reactions in severe drug hypersensitivity: infection or ongoing T‐cell hyperresponsiveness
Author(s) -
JörgWalther Lukas,
Schnyder Benno,
Helbling Arthur,
Helsing Karin,
Schüller Alexandra,
Wochner Annette,
Pichler Werner
Publication year - 2015
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.346
Subject(s) - medicine , hypersensitivity reaction , drug reaction , drug , dermatology , confusion , lymph node , immunology , pharmacology , psychology , psychoanalysis
Key Clinical Message “Flare‐up” reactions are late manifestations of severe T‐cell‐mediated drug hypersensitivity reactions. Management is anti‐inflammatory treatment and avoiding unnecessary medicines. Symptoms like fever, lymph node swelling, and blood count abnormalities may lead to confusion with bacterial infections. For prompt recognition it is important to keep the differential diagnosis in mind.