Open AccessP16 and HPV discordance in metastatic carcinoma of cervical lymph nodes of unknown primary
Author(s) -
Ralph Alyssa,
Meyer Andrew,
Sirota Ronald,
Hooberman Arthur
Publication year - 2015
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.338
Subject(s) - medicine , cervical lymph nodes , oncology , lymph , cervical carcinoma , immunohistochemistry , carcinoma , human papillomavirus , metastasis , cancer , pathology , cervical cancer
Key Clinical Message The prognostic utility of HPV in oropharyngeal squamous cell carcinoma ( OPSCC ) and non‐ OPSCC as has been well documented. Currently, a standardized IHC scoring system does not exist and is needed to define HPV positivity. We have recently seen a patient that provides a caution in using p16 status as a diagnostic aid.