Open AccessEffectiveness of low‐dose pasireotide in a patient with Cushing's disease: antiproliferative effect and predictivity of a short pasireotide suppression test
Author(s) -
Grossrubatscher Erika,
Zampetti Benedetta,
Dalino Ciaramella Paolo,
Doneda Paola,
Loli Paola
Publication year - 2015
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.321
Subject(s) - pasireotide , medicine , cushing's disease , clinical endpoint , oncology , disease , clinical trial , acromegaly , hormone , growth hormone
Key Clinical Message This case shows efficacy of low‐dose pasireotide in biochemical and clinical control of severe hypercortisolism and in tumor volume reduction in a patient with an ACTH ‐secreting macroadenoma. The drug may be an option for long‐term treatment in some patients where control of tumor mass is an important clinical endpoint.