Open AccessVariable linezolid exposure and response and the role of therapeutic drug monitoring: Case series
Author(s) -
Alghamdi Wael A.,
AlShaer Mohammad H.,
Klinker Kenneth P.,
Peloquin Charles A.
Publication year - 2020
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.2835
Subject(s) - linezolid , medicine , therapeutic drug monitoring , drug , intensive care medicine , renal function , pharmacology , staphylococcus aureus , vancomycin , biology , bacteria , genetics
Two patients with normal renal function, yet each showed unexpected, supra‐ and subtherapeutic linezolid plasma concentrations resulting in toxicity and ineffective therapy, respectively. TDM helps to early identify and correct such excursions.