Open AccessSuppression of postsurgical recurrence of hepatocellular carcinoma treated with autologous formalin‐fixed tumor vaccine, with special reference to glypican‐3
Author(s) -
Kawashima Issei,
Kawashima Yuri,
Matsuoka Yasuo,
Fujise Kiyotaka,
Sakai Hideki,
Takahashi Mari,
Yoshikawa Toshiaki,
Nakatsura Tetsuya,
Ishihara Takeshi,
Ohno Tadao
Publication year - 2015
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.279
Subject(s) - medicine , hepatocellular carcinoma , cirrhosis , glypican 3 , peripheral blood , gastroenterology , oncology
Key Clinical Message Autologous formalin‐fixed tumor vaccine ( AFTV ) suppressed re‐recurrence for more than 32 months of multiple‐recurrent hepatocellular carcinoma based on hepatitis C virus‐induced liver cirrhosis in a case with previous recurrence interval, 51‐, 28‐, 12‐, and 4‐months. We detected glypican‐3‐specific cytotoxic T lymphocytes in the peripheral blood at 12 months after AFTV .