Open AccessMacrogonadotropinoma, a venous thromboembolic event and asymptomatic extensive periventricular white matter changes in a patient with Klinefelter syndrome
Author(s) -
Namboodiri Divya,
Ng Hui Yi,
Zala Aakansha,
Magnussen John,
Davidson Andrew,
Champion Bernard,
Preda Veronica
Publication year - 2020
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.2714
Subject(s) - medicine , asymptomatic , klinefelter syndrome , white matter , cardiology , pediatrics , radiology , magnetic resonance imaging
Abstract Gonadotropinoma in Klinefelter syndrome (KS) is uncommon and may be a result of protracted stimulation of gonadotrophs from lack of androgen feedback. Associations of white matter changes and increased venous thromboembolic risk have been reported and need to be considered in patients with KS.