Open AccessHIV drug resistance mutations following poor adherence in HIV ‐infected patient: a case report
Author(s) -
Masikini Peter,
Mpondo Bonaventura C. T.
Publication year - 2015
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.254
Subject(s) - medicine , human immunodeficiency virus (hiv) , hiv drug resistance , drug resistance , viral load , drug , lentivirus , virology , antiretroviral therapy , pharmacology , microbiology and biotechnology , viral disease , biology
Key Clinical Message Acquired HIV drug resistance following poor adherence is common. We report a case of HIV ‐infected patient with poor CD 4 gain and self reported poor adherence. Investigations revealed high viral load and resistance to NRTI s and NNRTI s with sensitivity to boosted PI s. HIVDR mutations create treatment challenges in resource limited settings.