Open AccessDigynic triploidy: utility and challenges of noninvasive prenatal testing
Author(s) -
Fleischer Julie,
Shenoy Archana,
Goetzinger Katherine,
Cottrell Catherine E.,
Baldridge Dustin,
White Frances V.,
Shinawi Marwan
Publication year - 2015
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.247
Subject(s) - medicine , prenatal diagnosis , intensive care medicine , pregnancy , fetus , genetics , biology
Key Clinical Message Low fraction fetal DNA in noninvasive prenatal testing in the context of fetal growth restriction and multiple congenital anomalies should alert medical professionals to the possibility of digynic triploidy. Single‐nucleotide polymorphism microarray can detect the parental origin of triploidy and explain its mechanism.