Open AccessParvovirus B19‐induced hemophagocytic lymphohistiocytosis: Case report and review of the literature
Author(s) -
Kalmuk James,
Matar Sara,
Feng Gong,
Kilb Edward,
Lim Ming Y.
Publication year - 2019
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.2401
Subject(s) - medicine , hemophagocytic lymphohistiocytosis , serology , parvovirus , immunology , intensive care medicine , pediatrics , pathology , disease , antibody , virus
HLH is a catastrophic and likely underdiagnosed pathology with multiple triggers including infection. PVB19 can cause persistent marrow infection leading to HLH despite negative acute serologic markers making timely diagnosis difficult. Increased awareness of PVB19‐HLH is warranted given its potentially lethal nature and the careful interpretation required with serologic markers.