Open AccessA case of bony lytic lesions in a patient with Gaucher disease
Author(s) -
McGinnis Eric,
Moshref Razavi Habib
Publication year - 2019
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.2329
Subject(s) - medicine , disease , glucocerebroside , multiple myeloma , gaucher's disease , lytic cycle , enzyme replacement therapy , pathology , multisystem disease , plasma cell , monoclonal , monoclonal gammopathy of undetermined significance , glucocerebrosidase , immunology , monoclonal antibody , antibody , virus
Gaucher disease is a clinically heterogeneous disorder of glucocerebroside metabolism and may present incidentally late in life with unexplained thrombocytopenia, splenomegaly, or bony lesions. Clinicians should be aware that patients with Gaucher disease appear to have an increased risk for developing hematolymphoid malignancies, particularly monoclonal gammopathies and plasma cell myeloma.