Open AccessApoptosis of ileal crypt epithelia after allogeneic bone marrow transplantation without graft‐versus‐host disease
Author(s) -
Kreft Andreas,
Russo Alexandra,
Lux Steffi,
Waiz Lioudmila,
Seidmann Larissa,
Faber Jörg,
Kirkpatrick Charles J.
Publication year - 2015
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.227
Subject(s) - medicine , crypt , graft versus host disease , ileum , apoptosis , bone marrow , transplantation , disease , bone marrow transplantation , lymphoblastic leukemia , pathology , leukemia , immunology , biology , biochemistry
Key Clinical Message Intestinal crypt cell apoptosis may occur after allogeneic bone marrow transplantation without clinically overt graft‐versus‐host disease. We describe this phenomenon in a case of a 12‐year‐old girl who had segments of the ileum resected because of a relapse of acute lymphoblastic leukemia. The diagnostic difficulties are discussed.