Open AccessNon‐acute promyelocytic leukemia variant, acute myeloid leukemia with translocation (11;17)
Author(s) -
Altahan Rahaf,
Altahan Shatha,
Khalil Salem
Publication year - 2019
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.2044
Subject(s) - acute promyelocytic leukemia , myeloid leukemia , medicine , chromosomal translocation , acute leukemia , leukemia , promyelocytic leukemia protein , immunology , cancer research , gene , biology , genetics , retinoic acid
Key Clinical Message t(11;17) is a rare but recognized finding usually found in Acute Promyelocytic Leukemia with variant RARA translocation (APLv). We present a case of Acute Myeloid Leukemia with t(11;17) that has different break points than those occurring in APLv. The diagnosis of acute myeloid leukemia, not otherwise specified, acute monoblastic leukemia was reached after a thorough investigation. Reaching the correct diagnosis and distinguishing these two entities are essential as they have different management, prognosis, and overall survival.