
Can pulmonary sarcoidosis trigger a progressive multifocal leukoencephalopathy? Considerations from a case series and a review of literature
Author(s) -
Gamperl Irene,
Enzinger Christian,
Pichler Alexander,
Feichtinger Michael,
Schlager Thomas,
Fertl Elisabeth
Publication year - 2018
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.1816
Subject(s) - medicine , sarcoidosis , progressive multifocal leukoencephalopathy , leukoencephalopathy , slow virus , pulmonary sarcoidosis , multisystem disease , disease , pathology , immunology , dermatology , virus
Key Clinical Message Progressive multifocal leukoencephalopathy ( PML ) is a severe infectious brain disease with lethal outcome mainly seen in immunocompromised subjects. Herein, we describe a new form of PML with different outcome which was observed in patients suffering from systemic sarcoidosis. Thus, we raise the question whether preexisting sarcoidosis might predispose for or even trigger PML .