Open AccessFirst detection and molecular characterization of a DENV ‐1/ DENV ‐4 co‐infection during an epidemic in Rio de Janeiro, Brazil
Author(s) -
de BruyckerNogueira Fernanda,
Faria Nieli Rodrigues da Costa,
Nunes Priscila Conrado Guerra,
Nogueira Rita Maria Ribeiro,
de Filippis Ana Maria Bispo,
dos Santos Flavia Barreto
Publication year - 2018
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.1750
Subject(s) - dengue fever , dengue virus , serotype , virology , medicine , biology
Key Clinical Message In the 80s, dengue viruses type 1 and 4 ( DENV ‐1 and 4) were isolated in North region of Brazil. However, it was only after the DENV ‐1 introduction in the state of Rio de Janeiro ( RJ ) in mid‐1980s, that dengue became a nationwide public health problem. In 2009, this serotype re‐emerged causing an explosive epidemic in the country. DENV ‐4 was first detected in RJ in 2011 and in 2012, and DENV ‐1 and 4 were co‐circulating and responsible for a high number of cases notifications. Here, we describe the detection and molecular characterization of a DENV ‐1/4 co‐infection in sample of 2012 in RJ .