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Key Clinical Message  Calciphylaxis or calcific uremic arteriolopathy is a rare and serious disorder typically seen in patients with end‐stage renal disease that manifests as skin ischemia and necrosis and histologically characterized by calcification of dermal arterioles. Penis is a rare site of involvement and biopsy is not typically recommended, making the diagnosis clinico‐radiologic.

Penile lesion in a dialysis patient: Time to get an X‐ray