Open AccessGaucher disease and chronic myeloid leukemia: first reported patient receiving enzyme replacement and tyrosine kinase inhibitor therapies simultaneously
Author(s) -
Noya MSoledad,
AndradeCampos Marcio,
Irun Pilar,
López de Frutos Laura,
LópezFernandez MFernanda,
Giraldo Pilar
Publication year - 2018
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.1460
Subject(s) - medicine , enzyme replacement therapy , myeloid leukemia , disease , bone marrow , gaucher's disease , tyrosine kinase inhibitor , imatinib , cancer research , cancer
Key Clinical Message Report a female diagnosed as type 1 Gaucher disease after a femoral pathologic fracture when she was 55 years old. Enzyme replacement therapy was started, and she achieved therapeutic goals. In 2015, a Ph’ CML with numerous pseudo‐Gaucher cells in bone marrow appears. BCR/ABL was not present at GD diagnosis.