Open AccessA fatal case of primary cutaneous gamma–delta T‐cell lymphoma complicated by HLH and cardiac amyloidosis
Author(s) -
Gibson Juliet Fraser,
Kapur Lucy,
Sokhn Joseph,
Xu Mina,
Foss Francine M.
Publication year - 2015
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.142
Subject(s) - medicine , hemophagocytic lymphohistiocytosis , amyloidosis , lymphoma , cardiac amyloidosis , pathology , disease
Key Clinical Message Gamma–delta T‐cell lymphomas ( GD ‐ TCL ) are rare and rapidly fatal neoplasms that are often associated with Hemophagocytic Lymphohistiocytosis ( HLH ), a syndrome of fevers, cytopenias, and multiorgan failure that often leads to a rapid death. We report the first case demonstrating an association between GD ‐ TCL , HLH , and cardiac amyloidosis, presenting a novel mechanism for rapid deterioration in these patients.