Open AccessA new association – multiple endocrine neoplasia type 1 and malignant peripheral nerve sheath tumor
Author(s) -
Preda Veronica,
Sywak Mark,
Learoyd Diana
Publication year - 2015
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.139
Subject(s) - medicine , ganglioneuroma , multiple endocrine neoplasia , malignant peripheral nerve sheath tumor , pathology , nerve sheath neoplasm , endocrine system , adrenal gland , peripheral , neuroblastoma , neurofibromatosis , biochemistry , chemistry , genetics , biology , hormone , gene , cell culture
Key Clinical Message We report a patient with multiple endocrine neoplasia type 1 ( MEN‐1 ) and an aggressive malignant peripheral nerve sheath tumor (MPNST) arising from a ganglioneuroma of the adrenal gland. Patients with MEN‐1 require careful consideration of other tumor associations, including MPNST, as it can portend a poor prognosis. MEN‐1 and MPNST have not been reported.