Open AccessGranulomatous hypophysitis: rare disease with challenging diagnosis
Author(s) -
Elgamal Mohannad E.,
Mohamed Rawia M. H.,
Fiad Tarek,
Elgamal Essam A.
Publication year - 2017
Publication title -
clinical case reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.21
H-Index - 9
ISSN - 2050-0904
DOI - 10.1002/ccr3.1007
Subject(s) - medicine , histopathology , hypophysitis , pathology , pathological , giant cell , granulomatous disease , pituitary adenoma , granuloma , histopathological examination , disease , pituitary gland , adenoma , hormone
Key Clinical Message Granulomatous hypophysitis is rare pathology that mimics pituitary adenoma. Diagnosis is only confirmed by histopathology examination. Trans‐sphenoidal surgery is considered diagnostic when descent tissue specimen is obtained and therapeutic by decompressing optic pathway and the sella. Pathological findings always reveal granulomatous areas, multinucleated giant cells, plasma cells, and lymphocytes.