Premium
Production of Propane and Other Short‐Chain Alkanes by Structure‐Based Engineering of Ligand Specificity in Aldehyde‐Deformylating Oxygenase
Author(s) -
Khara Basile,
Me Navya,
Levy Colin,
Mansell David,
Das Debasis,
Marsh E. Neil G.,
Leys David,
Scrutton Nigel S.
Publication year - 2013
Publication title -
chembiochem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.05
H-Index - 126
eISSN - 1439-7633
pISSN - 1439-4227
DOI - 10.1002/cbic.201300307
Subject(s) - aldehyde , chemistry , metabolic engineering , biochemistry , oxygenase , aldehyde reductase , organic chemistry , enzyme , reductase , catalysis
Biocatalytic propane production: structure‐based engineering of aldehyde‐deformylating oxygenase improves specificity for short‐ and medium‐chain‐length aldehydes and enhances the propane generation in whole‐cell biotransformations. This presents new opportunities for developing biocatalytic modules for the production of volatile “drop‐in” biofuels.